How to Establish Clinical Prediction Models

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How to Establish Clinical Prediction Models

A clinical prediction model can be applied to several challenging clinical scenarios: screening high-risk individuals for asymptomatic disease, predicting future events such as disease or death, and assisting medical decision-making and health education. Despite the impact of clinical prediction models on practice, prediction modeling is a complex process requiring careful statistical analyses ...

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Clinical prediction in defined populations: a simulation study investigating when and how to aggregate existing models

BACKGROUND Clinical prediction models (CPMs) are increasingly deployed to support healthcare decisions but they are derived inconsistently, in part due to limited data. An emerging alternative is to aggregate existing CPMs developed for similar settings and outcomes. This simulation study aimed to investigate the impact of between-population-heterogeneity and sample size on aggregating existing...

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ژورنال

عنوان ژورنال: Endocrinology and Metabolism

سال: 2016

ISSN: 2093-596X,2093-5978

DOI: 10.3803/enm.2016.31.1.38